The Ultimate Guide To mif
The Ultimate Guide To mif
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The crystal constructions in the MIF-inhibitor complexes were being utilized since the Preliminary templates for Digital screening. The Protein planning Wizard module in Schrödinger was utilized to arrange Each and every MIF advanced. The ligand positioned in the Energetic web page in between chains A and B was managed. The sophisticated was then refined With all the OPLS pressure area [26]. Pro1, an important nucleophilic residue, was protonated according to experimental and theoretical results [27].
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